Benefits
Rapid onset of antibacterial action
Effective against severe and life-threatening infections
Useful in combination therapy for resistant organisms
Trusted aminoglycoside with well-established clinical use
BP-compliant formulation ensuring quality and safety
Usage Instructions
Administered intramuscularly or intravenously as directed by a healthcare professional
Dosage and duration depend on severity of infection, patient weight, renal function, and clinical response
Therapy should be monitored to avoid toxicity
For hospital and clinical use only
Mechanism of Action
Gentamicin acts by binding to the 30S subunit of bacterial ribosomes, inhibiting protein synthesis. This leads to the production of defective proteins and ultimately causes bacterial cell death, making it a bactericidal antibiotic.
Indications
Gentamicin Injection BP 80 mg/2 ml is indicated for the treatment of serious bacterial infections caused by susceptible organisms. It is commonly used in infections of the respiratory tract, urinary tract, bloodstream (septicemia), skin and soft tissues, bones and joints, and certain hospital-acquired infections.
Side Effects
Common or possible side effects may include:
Injection site pain or irritation
Nausea or vomiting
Headache or dizziness
Ototoxicity (hearing or balance disturbances)
Nephrotoxicity (changes in kidney function) with prolonged us
Precautions
Regular monitoring of renal function and hearing is advised
Use with caution in elderly patients
Avoid concurrent use with other nephrotoxic or ototoxic drugs
Ensure adequate hydration during therapy
Use strictly under medical supervision
Contraindications
Known hypersensitivity to gentamicin or other aminoglycoside antibiotics
Patients with a history of severe renal impairment unless strictly monitored
Pre-existing hearing or vestibular disorders
Use during pregnancy, unless clearly necessary and prescribed by a physician