Metoclopramide 5mg/ml

Antiemetic & Prokinetic Agent (Dopamine Antagonist)

An antiemetic (anti-vomiting) and prokinetic drug that speeds up gastric emptying and intestinal motility.

Key Information

Active Ingredient Metoclopramide Hydrochloride (5 mg/mL)

Dosage Form Injection

Pack Size 2 mL Ampoule

Storage Controlled room temperature. Protect from light.

Detailed Description

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Benefits

Rapid relief from nausea and vomiting

Improves gastric emptying and intestinal motility

Useful in chemotherapy- and postoperative-induced emesis

Helps manage migraine-associated nausea

Reliable and widely accepted antiemetic therapy

Usage Instructions

Administered intravenously or intramuscularly by a healthcare professional

Dosage and frequency depend on clinical indication, age, and patient condition

Slow IV administration is recommended to minimize adverse effects

For professional medical use only

Mechanism of Action

Metoclopramide works by blocking dopamine (D₂) receptors in the chemoreceptor trigger zone of the brain, thereby preventing nausea and vomiting. It also enhances acetylcholine release in the gastrointestinal tract, increasing gastric emptying and intestinal motility.

Indications

Metoclopramide Injection 5 mg/ml is indicated for the prevention and treatment of nausea and vomiting associated with gastrointestinal disorders, postoperative conditions, migraine attacks, chemotherapy, and radiotherapy. It is also used in conditions requiring enhancement of gastric motility.

Side Effects

Possible side effects may include:

Drowsiness or fatigue

Restlessness or agitation

Headache or dizziness

Diarrhea

Extrapyramidal reactions (especially with prolonged use)

Precautions

Use with caution in elderly patients and children

Avoid prolonged use to reduce risk of movement disorders

Caution in patients with renal or hepatic impairment

Monitor for signs of neurological adverse effects

Use only under medical supervision

Contraindications

Known hypersensitivity to metoclopramide or any component of the formulation

Gastrointestinal hemorrhage, obstruction, or perforation

History of epilepsy or seizure disorders

Pheochromocytoma

Patients with a history of tardive dyskinesia

Use in children below recommended age limits unless prescribed

Frequently Asked Questions

Find answers to common questions about Metoclopramide 5mg/ml

1 What is Metoclopramide Injection used for?

It is used to prevent and treat nausea and vomiting and to improve gastric motility.

2 Can Metoclopramide Injection be used after surgery?

Yes, it is commonly used to manage postoperative nausea and vomiting.

3 Is long-term use of Metoclopramide safe?

Long-term or high-dose use should be avoided due to the risk of neurological side effects.

4 Can this injection be used in children?

It may be used under strict medical supervision with appropriate dosing.

5 How quickly does Metoclopramide Injection work?

It generally acts quickly when administered parenterally, providing rapid symptom relief.