Gentamicin Sulphate BP 20mg/1ml

Aminoglycoside Antibiotic Broad-Spectrum Antibacterial Agent Anti-infective Drug

Gentamicin Sulphate BP 20 mg/1 mL Injection is a broad-spectrum aminoglycoside antibiotic used to treat serious bacterial infections caused by susceptible microorganisms. It works by inhibiting bacterial protein synthesis, which prevents bacteria from growing and multiplying. Gentamicin is effective against a wide range of Gram-negative and some Gram-positive bacteria. This injection is commonly used in hospitals to treat infections of the urinary tract, respiratory tract, bloodstream, bones, joints, and skin. It is often administered under medical supervision for moderate to severe infections where rapid antibacterial action is required.

Key Information

Active Ingredient Gentamicin Sulphate

Dosage Form Injection

Pack Size 2 × 5 Ampoules

Storage Store below 25°C.

Benefits

Gentamicin injection provides several therapeutic benefits:

Effective against serious bacterial infections

Provides rapid antibacterial action

Useful for hospital-acquired and severe infections

Helps eliminate infection-causing bacteria

Often used in combination therapy for severe infections

Usage Instructions

Gentamicin injection should be administered by a qualified healthcare professional.

It may be given intramuscularly (IM) or intravenously (IV) depending on the condition.

Dosage is determined based on patient weight, kidney function, and severity of infection.

Regular monitoring of kidney function and drug levels may be required during treatment.

Mechanism of Action

Gentamicin works by binding to the 30S ribosomal subunit of bacteria, which interferes with protein synthesis. This action leads to the production of defective bacterial proteins and eventual bacterial cell death, making it highly effective in treating severe bacterial infections.

Indications

Gentamicin Sulphate Injection is indicated for the treatment of:

Severe bacterial infections

Urinary tract infections (UTIs)

Respiratory tract infections

Septicemia (bloodstream infections)

Skin and soft tissue infections

Bone and joint infections

Intra-abdominal infections

Hospital-acquired infections

Side Effects

Some patients may experience side effects such as:

Pain or irritation at injection site

Nausea or vomiting

Kidney function changes

Hearing problems (rare but serious)

Dizziness

Skin rash or allergic reactions

Precautions

Use cautiously in patients with kidney disease.

Long-term use may cause hearing damage or kidney toxicity.

Regular monitoring of renal function and hearing is recommended.

Inform your doctor if you are taking other antibiotics or diuretics.

Contraindications

This medicine should not be used in the following conditions:

Hypersensitivity to gentamicin or other aminoglycoside antibiotics

Severe kidney impairment without proper monitoring

History of hearing loss caused by aminoglycosides

Patients with myasthenia gravis

Frequently Asked Questions

Find answers to common questions about Gentamicin Sulphate BP 20mg/1ml

1 What is Gentamicin Sulphate Injection 20 mg/1 mL used for?

It is used to treat serious bacterial infections such as UTIs, respiratory infections, and bloodstream infections.

2 How is Gentamicin injection administered?

It is administered intramuscularly or intravenously by a healthcare professional.

3 Can Gentamicin treat severe infections?

Yes, Gentamicin is commonly used for severe or hospital-acquired bacterial infections.

4 Does Gentamicin affect kidney function?

Yes, high doses or prolonged use may affect kidney function, so monitoring is required.

5 Can Gentamicin cause hearing problems?

In rare cases, prolonged use may lead to hearing loss or balance issues, especially at high doses.