Gentamicin Sulphate BP 40mg/1ml

Aminoglycoside Antibiotic Broad-Spectrum Antibacterial Agent Anti-infective Drug

Gentamicin Sulphate BP 40 mg/1 mL Injection is a broad-spectrum aminoglycoside antibiotic used to treat moderate to severe bacterial infections caused by susceptible microorganisms. It works by inhibiting bacterial protein synthesis, preventing bacteria from multiplying and spreading within the body. Gentamicin is effective against a wide range of Gram-negative and some Gram-positive bacteria, making it useful for treating infections of the urinary tract, respiratory tract, bloodstream, skin, bones, and joints. This injection is commonly used in hospital settings under medical supervision to provide rapid antibacterial action and effective infection control.

Key Information

Active Ingredient Gentamicin Sulphate

Dosage Form Injection

Pack Size 2 × 5 Ampoules

Storage Store below 25°C.

Benefits

Gentamicin injection offers several therapeutic benefits:

Effective against serious bacterial infections

Provides rapid antibacterial action

Helps eliminate infection-causing bacteria

Useful for hospital-acquired infections

Can be used in combination therapy for severe infections

Usage Instructions

This injection should be administered by a qualified healthcare professional.

It can be given intramuscularly (IM) or intravenously (IV) depending on the medical condition.

Dosage is determined based on patient weight, kidney function, and severity of infection.

Follow the prescribed treatment duration to ensure complete recovery.

Mechanism of Action

Gentamicin works by binding to the 30S ribosomal subunit of bacterial cells, which interferes with protein synthesis. This results in the production of defective proteins, leading to bacterial cell death and elimination of the infection.

Indications

Gentamicin Sulphate 40 mg/1 mL Injection is indicated for the treatment of:

Severe bacterial infections

Urinary tract infections (UTIs)

Respiratory tract infections

Septicemia (bloodstream infections)

Skin and soft tissue infections

Bone and joint infections

Intra-abdominal infections

Hospital-acquired infections

Side Effects

Some patients may experience side effects such as:

Pain or swelling at injection site

Nausea or vomiting

Dizziness

Kidney function changes

Hearing problems (rare)

Skin rash or allergic reactions

Precautions

Use cautiously in patients with kidney impairment.

Long-term or high-dose use may cause nephrotoxicity (kidney damage) or ototoxicity (hearing damage).

Regular monitoring of renal function and hearing ability is recommended during treatment.

Inform your doctor if you are taking diuretics or other antibiotics.

Contraindications

This medicine should not be used in the following conditions:

Hypersensitivity to gentamicin or other aminoglycoside antibiotics

Severe kidney disease without medical supervision

History of aminoglycoside-induced hearing loss

Patients suffering from myasthenia gravis

Frequently Asked Questions

Find answers to common questions about Gentamicin Sulphate BP 40mg/1ml

1 What is Gentamicin Sulphate 40 mg/1 mL Injection used for?

It is used to treat serious bacterial infections such as urinary tract infections, respiratory infections, and bloodstream infections.

2 How is Gentamicin injection administered?

It is administered intramuscularly or intravenously by a healthcare professional.

3 Can Gentamicin treat hospital-acquired infections?

Yes, it is commonly used to treat hospital-acquired and severe bacterial infections.

4 Can Gentamicin affect the kidneys?

Yes, prolonged use or high doses may affect kidney function, so medical monitoring is necessary.

5 Can Gentamicin cause hearing problems?

In rare cases, high doses or long-term use may lead to hearing loss or balance issues.