Metoclopramide Injection B.P. 10 mg/2 ml

Antiemetic Prokinetic Agent Dopamine Receptor Antagonist

Metoclopramide Injection B.P. 10 mg/2 mL is an antiemetic and prokinetic medication used to treat nausea, vomiting, and gastrointestinal motility disorders. It works by blocking dopamine receptors in the brain that trigger nausea and vomiting while also enhancing the movement of the stomach and intestines. This injection is commonly used in hospitals to manage postoperative nausea, chemotherapy-induced vomiting, migraine-associated nausea, and gastric motility disorders. Metoclopramide also helps improve gastric emptying and relieve symptoms related to gastroesophageal reflux disease (GERD) and diabetic gastroparesis.

Key Information

Active Ingredient Metoclopramide

Dosage Form Injection

Pack Size 2 × 10 ampoules

Storage Store below 25°C

Benefits

Metoclopramide injection provides several therapeutic benefits:

Effective relief from nausea and vomiting

Improves gastric emptying and digestion

Useful in postoperative and chemotherapy-induced nausea

Helps manage GERD-related symptoms

Provides rapid action when administered by injection

Usage Instructions

This injection should be administered by a qualified healthcare professional.

It may be given intravenously (IV) or intramuscularly (IM).

The dosage depends on the patient’s condition and doctor’s prescription.

Do not self-administer without medical supervision.

Mechanism of Action

Metoclopramide works by blocking dopamine D2 receptors in the chemoreceptor trigger zone (CTZ) of the brain, which suppresses the vomiting reflex. It also enhances acetylcholine activity in the gastrointestinal tract, improving gastric motility and accelerating gastric emptying.

Indications

Metoclopramide Injection 10 mg/2 mL is indicated for:

Nausea and vomiting

Postoperative nausea and vomiting

Chemotherapy-induced nausea

Migraine-associated nausea

Diabetic gastroparesis

Gastroesophageal reflux disease (GERD)

Gastric motility disorders

Side Effects

Some patients may experience side effects such as:

Drowsiness

Fatigue

Restlessness

Diarrhea

Muscle spasms (rare)

Precautions

Use cautiously in patients with kidney disease.

Avoid alcohol while receiving this medication.

Inform the doctor if you have neurological disorders.

Use during pregnancy or breastfeeding only if prescribed by a doctor.

Contraindications

This medicine should not be used in the following conditions:

Hypersensitivity to metoclopramide

Gastrointestinal obstruction or bleeding

Epilepsy or seizure disorders

Parkinson’s disease

Pheochromocytoma

Frequently Asked Questions

Find answers to common questions about Metoclopramide Injection B.P. 10 mg/2 ml

1 What is Metoclopramide Injection used for?

It is used to treat nausea, vomiting, and gastric motility disorders.

2 How is Metoclopramide injection administered?

It is administered by a healthcare professional through intravenous (IV) or intramuscular (IM) injection.

3 Can Metoclopramide help with postoperative nausea?

Yes, it is commonly used to prevent and treat nausea and vomiting after surgery.

4 Does Metoclopramide improve digestion?

Yes, it helps improve stomach emptying and gastrointestinal motility.

5 What are common side effects of Metoclopramide injection?

Common side effects include drowsiness, fatigue, restlessness, and diarrhea.