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Imipenem & Cilastatin for Injection U.S.P. is a broad-spectrum carbapenem antibiotic combination used for the treatment of severe and life-threatening bacterial infections. Imipenem provides powerful antibacterial activity by inhibiting bacterial cell wall synthesis, while Cilastatin prevents the renal metabolism of imipenem, ensuring higher and sustained drug levels in the body. This combination is commonly used in hospital settings for resistant and complicated infections under strict medical supervision.