Cefoperazone & Sulbactam 2000 mg

Cephalosporin Antibiotic Beta-Lactamase Inhibitor Combination Broad-Spectrum Antibacterial Agent

Cefoperazone & Sulbactam 2000 mg Injection is a broad-spectrum antibiotic combination used for the treatment of moderate to severe bacterial infections. Cefoperazone is a third-generation cephalosporin antibiotic that kills bacteria by inhibiting bacterial cell wall synthesis, while sulbactam is a beta-lactamase inhibitor that prevents the breakdown of cefoperazone by resistant bacteria. This combination enhances the effectiveness of the antibiotic against a wide range of Gram-positive and Gram-negative organisms. It is widely used in hospitals for the treatment of respiratory tract infections, urinary tract infections, intra-abdominal infections, septicemia, and skin infections.

Key Information

Active Ingredient Cefoperazone, Sulbactam

Dosage Form Dry Injection

Pack Size 1 Vial 2000 mg

Storage Store below 25°C. Protect from moisture and direct sunlight.

Benefits

Cefoperazone & Sulbactam injection provides several benefits:

Broad-spectrum activity against various bacteria

Effective for severe and hospital-acquired infections

Sulbactam helps overcome bacterial resistance

Provides rapid bacterial killing

Suitable for serious infections requiring injectable antibiotics

Usage Instructions

Administered intravenously (IV) or intramuscularly (IM) by a healthcare professional.

Dosage depends on the type and severity of infection.

Treatment duration should follow medical advice.

Do not self-administer.

Mechanism of Action

Cefoperazone works by inhibiting bacterial cell wall synthesis, which causes bacterial cell death. Sulbactam inhibits beta-lactamase enzymes produced by resistant bacteria, protecting cefoperazone from degradation and improving its antibacterial activity.

Indications

Cefoperazone & Sulbactam Injection is indicated for:

Respiratory tract infections

Urinary tract infections (UTI)

Intra-abdominal infections

Skin and soft tissue infections

Gynecological infections

Septicemia (bloodstream infections)

Bone and joint infections

Side Effects

Some possible side effects include:

Nausea

Diarrhea

Headache

Injection site pain or swelling

Allergic reactions such as rash or itching

Serious reactions require immediate medical attention.

Precautions

Inform the doctor if you have allergies to antibiotics.

Use cautiously in patients with liver or kidney disease.

Avoid alcohol during treatment as it may cause disulfiram-like reaction with cefoperazone.

Use during pregnancy or breastfeeding only if prescribed.

Contraindications

This medicine should not be used in the following conditions:

Hypersensitivity to cephalosporin antibiotics

Allergy to penicillin or beta-lactam antibiotics

Severe liver impairment without medical supervision

Frequently Asked Questions

Find answers to common questions about Cefoperazone & Sulbactam 2000 mg

1 What is Cefoperazone & Sulbactam 2000 mg injection used for?

It is used to treat serious bacterial infections such as respiratory, urinary tract, abdominal, and bloodstream infections.

2 How is Cefoperazone & Sulbactam injection administered?

It is given intravenously (IV) or intramuscularly (IM) by a healthcare professional.

3 Why is Sulbactam added to Cefoperazone?

Sulbactam blocks beta-lactamase enzymes, allowing cefoperazone to work effectively against resistant bacteria.

4 Can this injection treat severe infections?

Yes, it is commonly used in hospital settings for moderate to severe infections.

5 What are the common side effects?

Common side effects include nausea, diarrhea, headache, and injection site pain.