Suxamethonium Chloride Injection BP 100mg/2mL

Depolarizing Neuromuscular Blocking Agent

Short-term muscle relaxation for intubation or ECT.

Key Information

Active Ingredient Suxamethonium Chloride

Dosage Form Injection

Pack Size 2mL, 5mL, 10mL Amp/Vial

Storage 2°C - 8°C (Refrigerate)

Benefits

Extremely rapid onset of action

Short duration of muscle paralysis

Ideal for emergency airway management

Facilitates smooth and quick intubation

Useful in short surgical and diagnostic procedures

Usage Instructions

Administer intravenously by an experienced anesthesiologist or trained medical professional

Dosage is individualized based on patient weight and clinical condition

Continuous monitoring of respiratory and cardiovascular status is mandatory

Mechanism of Action

Suxamethonium acts as a depolarizing neuromuscular blocker by mimicking acetylcholine at the neuromuscular junction. It causes sustained depolarization of the muscle end-plate, leading to temporary muscle paralysis.

Indications

Suxamethonium Chloride Injection BP is indicated for:

Rapid sequence intubation (RSI)

Short-term skeletal muscle relaxation

Facilitation of endotracheal intubation

Prevention of injury during electroconvulsive therapy (ECT)

Muscle relaxation during short surgical or diagnostic procedures

Side Effects

Common side effects:

Muscle fasciculations

Bradycardia or tachycardia

Increased intraocular or intragastric pressure

Precautions

Facilities for airway management and mechanical ventilation must be available

Use with caution in pediatric and elderly patients

Monitor serum potassium levels in high-risk patients

Avoid repeated doses unless clearly indicated

Use with caution in patients with liver disease or enzyme deficiencies

Contraindications

Suxamethonium Chloride Injection is contraindicated in patients with:

Known hypersensitivity to suxamethonium

History or risk of malignant hyperthermia

Hyperkalemia or conditions predisposing to elevated serum potassium

Neuromuscular disorders (e.g., muscular dystrophy)

Severe burns, crush injuries, or prolonged immobilization

Pseudocholinesterase deficiency

Frequently Asked Questions

Find answers to common questions about Suxamethonium Chloride Injection BP 100mg/2mL

1 What is Suxamethonium Chloride Injection used for?

It is primarily used for rapid muscle relaxation during intubation and short procedures.

2 How fast does it act?

It acts within 30–60 seconds after intravenous administration.

3 How long does its effect last?

The muscle-relaxant effect usually lasts 5–10 minutes.

4 Can Suxamethonium cause serious side effects?

Yes, including hyperkalemia and malignant hyperthermia, which require immediate medical management.

5 Is Suxamethonium suitable for long-term muscle relaxation?

No, it is intended only for short-term use due to its rapid onset and short duration.