Ranitidine Injection BP 25mg/mL

H2-Receptor Antagonist (Gastric Acid Suppressant)

Ranitidine Injection BP 25 mg/mL is a sterile parenteral formulation of an H2-receptor antagonist that reduces gastric acid secretion. It is commonly used in hospital settings for patients who require rapid control of acid-related disorders or when oral administration is not feasible. Manufactured in accordance with British Pharmacopoeia (BP) standards, this injection ensures pharmaceutical-grade quality, safety, and therapeutic reliability. It is designed for intravenous or intramuscular administration under professional medical supervision.

Key Information

Active Ingredient Ranitidine 25mg/mL

Dosage Form Injection

Pack Size 2mL Ampoule

Storage 15°C - 30°C (Protect from light)

Benefits

Rapid reduction of gastric acid secretion

Effective management of ulcer-related conditions

Suitable for hospitalized and critically ill patients

Helps prevent stress-related gastric complications

BP-compliant formulation ensuring quality standards

Usage Instructions

Administered intravenously (slow injection or infusion) or intramuscularly

Dosage depends on clinical indication and patient condition

For professional medical use only

Adjust dosage in patients with renal impairment

Mechanism of Action

Ranitidine works by blocking histamine H2 receptors in the gastric parietal cells, thereby reducing the secretion of gastric acid. This helps promote healing of ulcers and reduces irritation of the gastrointestinal lining.

Indications

Ranitidine Injection BP 25 mg/mL is indicated for:

Peptic ulcer disease (gastric and duodenal ulcers)

Gastroesophageal reflux disease (GERD)

Hypersecretory conditions such as Zollinger–Ellison syndrome

Prevention of stress ulcers in hospitalized patients

Management of upper gastrointestinal bleeding (as adjunct therapy)

Preoperative reduction of gastric acid secretion

Side Effects

Possible side effects may include:

Headache

Dizziness

Constipation or diarrhea

Injection site reactions

Rare: Allergic reactions or cardiac rhythm disturbances

Precautions

Use cautiously in patients with renal impairment

Monitor liver function in prolonged therapy

Evaluate persistent gastric symptoms to rule out malignancy

Use under strict medical supervision

Caution in elderly patients

Contraindications

Known hypersensitivity to ranitidine or other H2-receptor antagonists

History of severe allergic reactions to similar medications

Use with caution in patients with acute porphyria

Frequently Asked Questions

Find answers to common questions about Ranitidine Injection BP 25mg/mL

1 What is Ranitidine Injection BP used for?

It is used to reduce stomach acid production in ulcer disease, GERD, and stress-related gastric conditions.

2 When is the injection preferred over tablets?

It is preferred when oral administration is not possible or rapid acid control is required.

3 Is this product BP compliant?

Yes, it is manufactured according to British Pharmacopoeia standards.

4 Can it be used in ICU patients?

Yes, it is often used in hospitalized or critically ill patients to prevent stress ulcers.

5 Does it require dose adjustment?

Dose adjustment may be necessary in patients with renal impairment.