Local Anesthetic Combo

Lidocaine and Adrenaline Injection BP 20mg+1mg /mL

Local Anesthetic Combination – Amide Anesthetic with Vasoconstrictor

Lidocaine and Adrenaline Injection BP is a sterile combination anesthetic solution manufactured in compliance with British Pharmacopoeia (BP) standards. It combines the rapid-onset local anesthetic effect of lidocaine with the vasoconstrictive properties of adrenaline.

Key Information

Active Ingredient Lidocaine 20mg + Adrenaline 1mg/mL
Dosage Form Injection
Pack Size 2mL Amp, 30mL Vial
Storage 15°C - 25°C (Protect from light)

Benefits

Rapid onset of local anesthesia

Prolonged duration of action

Reduced intraoperative bleeding

Lower systemic toxicity risk due to slower absorption

BP-compliant sterile injectable formulation

Ideal for hospital and dental clinic use

Usage Instructions

Administered by trained healthcare professionals only

Intended for local infiltration or nerve block anesthesia

Dosage depends on procedure type and patient condition

Aspirate before injection to avoid intravascular administration

Continuous monitoring recommended in high-risk patients

Mechanism of Action

Lidocaine works by blocking sodium channels in nerve membranes, preventing nerve impulse conduction and producing local anesthesia.
Adrenaline (epinephrine) acts on alpha-adrenergic receptors, causing vasoconstriction. This reduces blood flow at the injection site, prolongs anesthetic effect, and minimizes systemic absorption.

Indications

Lidocaine and Adrenaline Injection BP 20mg + 1mg/mL is indicated for:

Local anesthesia in minor surgical procedures

Dental procedures requiring local anesthesia

Dermatological procedures

Suturing and wound management

Regional nerve blocks

Minor orthopedic procedures

Side Effects

Possible side effects may include:

Local swelling or redness

Palpitations

Increased heart rate

Hypertension

Dizziness

Rare allergic reactions

CNS symptoms in case of overdose

Precautions

Use cautiously in patients with cardiovascular disease

Avoid use in areas with end-arterial blood supply

Monitor patients with hypertension or thyroid disorders

Use lowest effective dose

Strict aseptic technique required

Contraindications

Hypersensitivity to lidocaine or amide-type local anesthetics

Hypersensitivity to adrenaline (epinephrine)

Severe cardiac arrhythmias

Uncontrolled hypertension

Hyperthyroidism (use with caution)

Injection into end-arterial areas (e.g., fingers, toes, ears, nose, penis) where vasoconstriction may cause ischemia

Frequently Asked Questions

Find answers to common questions about Lidocaine and Adrenaline Injection BP 20mg+1mg /mL

1 Why is adrenaline added to lidocaine?
Adrenaline prolongs the anesthetic effect and reduces bleeding during procedures.
2 Is this injection used in dental procedures?
Yes, it is commonly used in dental and minor surgical procedures.
3 Can it affect heart rate?
Yes, adrenaline may increase heart rate and blood pressure in some patients.
4 Is this BP compliant?
Yes, it is manufactured according to British Pharmacopoeia standards.
5 Who should administer this injection?
It must be administered by qualified healthcare professionals only.
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