Iron Sucrose Injection USP 100mg/5mL

Parenteral Iron Preparation – Hematinic

Iron Sucrose Injection USP 100mg/5mL is a sterile intravenous iron preparation manufactured in compliance with United States Pharmacopeia (USP) standards. It is designed for rapid and controlled replenishment of iron stores in patients with iron deficiency anemia. Iron sucrose is a stable iron-carbohydrate complex that allows gradual release of elemental iron for hemoglobin synthesis. It is widely used in nephrology, gynecology, obstetrics, and general medicine settings, particularly in patients who cannot tolerate or respond adequately to oral iron therapy. This formulation ensures high bioavailability, predictable response, and suitability for hospital-based intravenous administration.

Key Information

Active Ingredient Iron as Iron Sucrose 20mg/mL

Dosage Form Injection

Pack Size 2.5mL, 5mL Vial

Storage 15°C - 25°C (Do not freeze)

Benefits

Rapid correction of iron deficiency anemia

Suitable for patients intolerant to oral iron

High safety and tolerability profile

Supports hemoglobin synthesis

USP-compliant sterile injectable formulation

Ideal for CKD and dialysis patients

Usage Instructions

Administered intravenously (IV) only by healthcare professionals

May be given as slow IV injection or IV infusion

Dosage depends on calculated iron deficit and clinical condition

Monitor patient during administration for hypersensitivity reactions

Mechanism of Action

Iron sucrose delivers elemental iron directly into the bloodstream. The iron complex is taken up by the reticuloendothelial system, where iron is released and incorporated into hemoglobin and other iron-containing proteins, restoring iron stores and improving oxygen transport capacity.

Indications

Iron Sucrose Injection USP 100mg/5mL is indicated for:

Iron deficiency anemia (IDA)

Anemia associated with chronic kidney disease (CKD)

Postpartum anemia

Preoperative anemia management

Anemia in patients intolerant to oral iron therapy

Nutritional iron deficiency requiring intravenous therapy

Side Effects

Possible side effects include:

Injection site reactions

Hypotension

Nausea

Headache

Muscle cramps

Rare hypersensitivity reactions

Precautions

Administer under medical supervision with resuscitation facilities available

Monitor hemoglobin and ferritin levels during therapy

Avoid use in patients with iron overload

Use cautiously in patients with hepatic impairment

Contraindications

Hypersensitivity to iron sucrose or other parenteral iron preparations

Iron overload disorders (e.g., hemochromatosis)

Anemia not caused by iron deficiency

First trimester of pregnancy (unless clearly indicated)

Frequently Asked Questions

Find answers to common questions about Iron Sucrose Injection USP 100mg/5mL

1 What is Iron Sucrose Injection used for?

It is used to treat iron deficiency anemia, especially in patients with chronic kidney disease or intolerance to oral iron.

2 How quickly does it improve hemoglobin levels?

Hemoglobin levels generally improve within a few weeks of therapy.

3 Can it be given during dialysis?

Yes, it is commonly administered to CKD patients undergoing dialysis.

4 Is it better than oral iron?

It is preferred when oral iron is ineffective or not tolerated.

5 Is this product USP compliant?

Yes, it is manufactured according to United States Pharmacopeia standards.