Gentamicin Injection BP 40mg/mL

Antibiotic – Aminoglycoside

Gentamicin Injection BP 40mg/mL is a sterile, broad-spectrum aminoglycoside antibiotic manufactured according to British Pharmacopoeia (BP) standards. It is effective against a wide range of Gram-negative bacteria and certain Gram-positive organisms. This injectable formulation is widely used in hospital, ICU, neonatal, and surgical settings for the management of serious systemic infections. It may be used alone or in combination with other antibiotics for synergistic antibacterial action. Gentamicin Injection BP ensures high-quality standards, potency, and stability suitable for hospital and clinical use.

Key Information

Active Ingredient Gentamicin Sulphate

Dosage Form Injection

Pack Size 1mL, 2mL Ampoule

Storage 15°C - 30°C

Benefits

Broad-spectrum antibacterial activity

Effective against severe and life-threatening infections

Rapid bactericidal action

Suitable for hospital and critical care settings

BP-compliant sterile injectable formulation

Usage Instructions

Administered intravenously (IV) or intramuscularly (IM) by healthcare professionals

Dosage based on body weight, renal function, and infection severity

Therapeutic drug monitoring recommended

Monitor renal function and hearing during therapy

Mechanism of Action

Gentamicin binds to the 30S ribosomal subunit of bacteria, inhibiting protein synthesis and leading to bacterial cell death. It is bactericidal in nature.

Indications

Gentamicin Injection BP 40mg/mL is indicated for the treatment of serious bacterial infections such as:

Septicemia

Lower respiratory tract infections

Urinary tract infections (UTIs)

Intra-abdominal infections

Skin and soft tissue infections

Bone and joint infections

Neonatal infections

Postoperative infections

Side Effects

Possible side effects include:

Nephrotoxicity

Ototoxicity (hearing loss or balance issues)

Injection site pain

Nausea

Rare allergic reactions

Precautions

Monitor renal function regularly

Adjust dose in patients with renal impairment

Avoid prolonged therapy when possible

Use cautiously in elderly and neonatal patients

Avoid concurrent use with other nephrotoxic drugs

Contraindications

Hypersensitivity to gentamicin or other aminoglycosides

History of aminoglycoside-induced ototoxicity

Severe renal impairment (without monitoring)

Myasthenia gravis (use with caution)

Frequently Asked Questions

Find answers to common questions about Gentamicin Injection BP 40mg/mL

1 What is Gentamicin Injection BP used for?

It is used to treat serious bacterial infections such as septicemia, UTIs, and respiratory infections.

2 Is it effective against Gram-negative bacteria?

Yes, it is particularly effective against Gram-negative organisms.

3 Does it require monitoring?

Yes, kidney function and drug levels should be monitored during treatment.

4 Can it cause hearing problems?

Ototoxicity is a known risk, especially with prolonged use or high doses.

5 Is this product BP compliant?

Yes, it is manufactured according to British Pharmacopoeia standards.