Gentamicin Injection BP 20mg/mL

Antibiotic – Aminoglycoside

Gentamicin Injection BP 20mg/mL is a broad-spectrum aminoglycoside antibiotic designed for parenteral administration in hospital settings. It is effective against various Gram-negative bacteria and certain Gram-positive organisms. This sterile injectable formulation ensures rapid systemic action, making it suitable for moderate to severe infections requiring immediate therapeutic intervention. It is widely used in ICU, emergency, and inpatient departments. Manufactured as per BP standards, this injectable antibiotic ensures quality, sterility, and therapeutic reliability.

Key Information

Active Ingredient Gentamicin Sulphate

Dosage Form Injection

Pack Size 1mL, 2mL Ampoule

Storage 15°C - 30°C

Benefits

Effective against serious Gram-negative infections

Rapid bactericidal action

Suitable for combination antibiotic therapy

Reliable hospital-grade sterile injectable

Proven efficacy in neonatal and adult infections

Usage Instructions

Administer under medical supervision only.

Dosage is based on body weight, infection severity, and renal function.

Renal function monitoring is essential during therapy.

Therapeutic drug monitoring may be recommended for prolonged use.

Mechanism of Action

Gentamicin binds to the 30S ribosomal subunit of bacteria, inhibiting protein synthesis and leading to bacterial cell death. It exhibits bactericidal activity.

Indications

Gentamicin Injection BP 20mg/mL is indicated for the treatment of serious bacterial infections caused by susceptible organisms, including:

Septicemia (bloodstream infections)

Respiratory tract infections

Urinary tract infections (UTIs)

Intra-abdominal infections

Skin and soft tissue infections

Bone and joint infections

Neonatal infections

It is commonly used in combination therapy for severe hospital-acquired infections.

Side Effects

Common side effects:

Injection site reactions

Nausea

Mild rash

Precautions

Monitor renal function regularly

Assess hearing function in prolonged therapy

Dose adjustment required in renal impairment

Avoid concurrent use with other nephrotoxic or ototoxic drugs

Use cautiously in elderly patients

Contraindications

Hypersensitivity to gentamicin or other aminoglycosides

History of severe aminoglycoside-induced ototoxicity

Caution in patients with renal impairment

Frequently Asked Questions

Find answers to common questions about Gentamicin Injection BP 20mg/mL

1 What is Gentamicin Injection used for?

It is used to treat serious bacterial infections, especially Gram-negative infections.

2 Is monitoring required during treatment?

Yes, kidney function and sometimes drug levels should be monitored.

3 Can it be used in newborns?

Yes, under strict medical supervision and appropriate dosing.

4 Does it treat viral infections?

No, it is effective only against bacterial infections.

5 Is it suitable for outpatient use?

It is generally administered in hospital settings.