Chloroquine Phosphate Injection 200mg/5mL

Antimalarial Agent Antiprotozoal Drug

Chloroquine Phosphate Injection 200mg/5mL is an antimalarial injectable medication used in the treatment and management of malaria caused by susceptible strains of Plasmodium parasites. It is particularly useful in clinical situations where oral therapy is not possible or when rapid therapeutic action is required. Chloroquine works by interfering with the parasite's ability to digest hemoglobin within red blood cells, leading to the accumulation of toxic substances that destroy the malaria parasite. This injectable formulation provides rapid systemic availability, making it suitable for hospital and emergency treatment of severe malaria infections. Manufactured under strict pharmaceutical quality standards, it ensures sterility, stability, and consistent therapeutic effectiveness.

Key Information

Active Ingredient Chloroquine Phosphate 40mg/mL

Dosage Form Injection

Pack Size 5mL, 30mL Vial

Storage Below 30°C

Benefits

Effective treatment for susceptible malaria infections

Rapid onset of therapeutic action

Useful when oral therapy is not possible

Reliable injectable formulation for hospital use

Helps control malaria-related symptoms and complications

Usage Instructions

Administer only by qualified healthcare professionals.

May be given via intravenous or intramuscular injection as prescribed.

Dosage depends on the patient's body weight, severity of infection, and physician guidance.

Continuous monitoring is recommended during administration.

Mechanism of Action

Chloroquine accumulates in the acidic food vacuole of the malaria parasite within infected red blood cells.

Its actions include:

Inhibition of heme polymerase enzyme

Accumulation of toxic heme products

Destruction of the malaria parasite

This process ultimately kills the parasite and helps control the infection.

Indications

Chloroquine Phosphate Injection may be indicated for:

Treatment of malaria caused by susceptible Plasmodium species

Acute malaria infections when oral treatment is not feasible

Severe malaria cases requiring hospital management

Prophylaxis in certain malaria-endemic situations (as per medical advice)

Side Effects

Nausea

Headache

Dizziness

Injection site discomfort

Precautions

Monitor cardiac function during high-dose administration

Use cautiously in patients with liver impairment

Avoid overdose due to risk of toxicity

Monitor vision during prolonged therapy

Use with caution in patients with epilepsy

Contraindications

Hypersensitivity to chloroquine or related compounds

Patients with retinal or visual field changes due to antimalarial drugs

Severe liver disease (use with caution)

Frequently Asked Questions

Find answers to common questions about Chloroquine Phosphate Injection 200mg/5mL

1 What is Chloroquine Injection used for?

It is used for the treatment of malaria caused by susceptible parasites when rapid treatment is required.

2 Can it be used if oral medication cannot be taken?

Yes, injectable chloroquine is often used when oral therapy is not possible.

3 Does this injection treat all malaria types?

It is effective against chloroquine-sensitive malaria parasites; resistance may occur in some regions.

4 Should this injection be administered at home?

No, it should be administered only by trained healthcare professionals in clinical settings.