Bupivacaine Hydrochloride Injection USP 25mg/5mL

Local Anesthetic Amide-Type Regional Anesthetic Surgical Anesthesia Agent

Bupivacaine Hydrochloride Injection USP 25mg/5mL is a long-acting local anesthetic used to provide regional anesthesia and pain relief during surgical procedures, labor, and various medical interventions. It belongs to the amide class of local anesthetics and works by temporarily blocking nerve impulse conduction. This injectable formulation is widely used in epidural anesthesia, spinal anesthesia, and peripheral nerve blocks, providing prolonged anesthesia and effective pain control. Its extended duration of action makes it suitable for procedures requiring sustained analgesia. Manufactured under strict pharmaceutical quality standards, Bupivacaine Injection ensures sterility, stability, and consistent anesthetic performance, making it suitable for hospital and surgical settings.

Key Information

Active Ingredient Bupivacaine HCl 5mg/mL

Dosage Form Injection

Pack Size 1mL, 2mL, 4mL, 5mL, 10mL, 20mL

Storage 15°C - 30°C

Benefits

Long-lasting anesthesia and pain relief

Effective for surgical and obstetric procedures

Suitable for regional and nerve block anesthesia

Provides reliable pain control during and after surgery

Widely used in hospital and clinical anesthesia practice

Usage Instructions

Administer only by trained healthcare professionals experienced in regional anesthesia techniques.

The dosage depends on the type of anesthesia, patient condition, and clinical procedure.

Continuous monitoring of cardiovascular and neurological status is recommended during administration.

Mechanism of Action

Bupivacaine works by blocking voltage-gated sodium channels in nerve membranes.

This action prevents the initiation and conduction of nerve impulses, resulting in:

Loss of sensation in the targeted area

Temporary nerve conduction blockade

Effective local or regional anesthesia

The anesthetic effect persists until the drug is gradually metabolized and cleared from the body.

Indications

Bupivacaine Hydrochloride Injection may be used for:

Epidural anesthesia during surgery

Spinal anesthesia

Peripheral nerve block procedures

Local infiltration anesthesia

Pain management during labor and delivery

Postoperative pain control

Side Effects

Injection site pain

Nausea

Dizziness

Precautions

Use cautiously in patients with cardiovascular disease

Monitor for signs of local anesthetic systemic toxicity

Careful dose calculation is required to prevent overdose

Use cautiously in elderly or debilitated patients

Ensure proper resuscitation equipment is available during administration

Contraindications

Hypersensitivity to bupivacaine or other amide-type local anesthetics

Severe hypotension or shock

Infection at the injection site

Certain cardiac conduction disorders

Frequently Asked Questions

Find answers to common questions about Bupivacaine Hydrochloride Injection USP 25mg/5mL

1 What is Bupivacaine Injection used for?

is used to produce regional or local anesthesia during surgical procedures and medical interventions.

2 Is Bupivacaine long-acting?

Yes, it provides longer duration of anesthesia compared to many other local anesthetics.

3 Can this injection be used during labor?

Yes, it is commonly used for epidural anesthesia during labor under medical supervision.

4 Who should administer Bupivacaine Injection?

It should only be administered by trained healthcare professionals experienced in anesthesia techniques.